Values are mean ± S.E. (n).
Article: NMDA receptor function in mouse models of Huntington disease.
Full Text (publisher's website) ; Article Metadata ; Article Data (extracted) Cepeda C; Ariano MA; Calvert CR; Flores-Hernández J; Chandler SH; Leavitt BR; Hayden MR; Levine MS J. Neurosci. Res., 2001
WT | R6/2-Presymptomatic | WT | R6/2-Symptomatic | |
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| ||||
NMDA current and current density | ||||
NMDA current (pA) | 166 ± 44 (10) | 368 ± 106 (22) P < 0.05 | 237 ± 38 (15) | 356 ± 96 (14) |
Current density (pA/pF) | 1.9 ± 0.3 (10) | 4.3 ± 1.2 (22) P < 0.05 | 2.9 ± 0.4 (15) | 5.7 ± 1.6 (14) P < 0.05 |
Time to peak NMDA current (sec) | 291 ± 24 (10) | 312 ± 24 (20) | 226 ± 9 (15) | 227 ± 11 (14) |
Peak Ca2+ concentration in response to NMDA | ||||
% Ca2+ change (ΔF/F) | 19 ± 3 (6) | 36 ± 7 (12) P < 0.05 | 31 ± 4 (15) | 91 ± 32 (13) P < 0.05 |
% Ca2+ change (nM) | 23 ± 3 (6) | 44 ± 9 (12) P < 0.05 | 37 ± 6 (15) | 131 ± 55 (13) P < 0.05 |
Time to peak Ca2+ influx (sec) | 294 ± 31 (6) | 304 ± 34 (12) | 244 ± 11 (15) | 249 ± 12 (13) |
Inferred neuron-electrophysiology data values
Neuron Type | Neuron Description | Ephys Prop | Extracted Value | Standardized Value | Content Source |
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